Name: Southern Brisket Grilled Cheese Recipe
Prep time: 10 min
Cook time: 10 min
Total time: 20 min
Cuisine: Southern
Ingredients: 8 slices thick-cut white bread or Texas toast; 2 tablespoons butter, softened; 1/2 pound cooked beef brisket, shredded or chopped; 1 cup shredded sharp cheddar cheese; 1/2 cup shredded Monterey Jack cheese; 1/4 cup barbecue sauce, plus more for dipping; 1/4 small red onion, thinly sliced (optional); 1 tablespoon pickled jalapeños (optional)

Description

This Southern Brisket Grilled Cheese combines tender, smoky brisket with melted cheddar and Monterey Jack cheeses between buttery toasted slices of thick-cut white bread. Enhanced with tangy barbecue sauce, optional red onions, and pickled jalapeños, this sandwich offers a perfect balance of smoky, cheesy, and spicy flavors. Perfect for a comforting main course ready in just 20 minutes.

Ingredients

Scale

Bread and Butter

8 slices thick-cut white bread or Texas toast
2 tablespoons butter, softened

Filling

1/2 pound cooked beef brisket, shredded or chopped
1 cup shredded sharp cheddar cheese
1/2 cup shredded Monterey Jack cheese
1/4 cup barbecue sauce, plus more for dipping
1/4 small red onion, thinly sliced (optional)
1 tablespoon pickled jalapeños (optional)

Cook Mode Prevent your screen from going dark

Instructions

Prepare the Bread: Butter one side of each slice of bread evenly to ensure a golden, crispy exterior when grilled.
Assemble the Sandwiches: Lay 4 slices of bread butter-side down on a clean surface. Evenly layer cheddar and Monterey Jack cheeses over the bread. Add a generous portion of chopped brisket atop the cheese. Drizzle with 1/4 cup of barbecue sauce, then add red onion slices and pickled jalapeños if using. Sprinkle remaining cheese on top of the fillings and cover each with another slice of bread, butter-side up.
Heat the Skillet: Warm a large skillet or griddle over medium heat to prepare for grilling.
Grill the Sandwiches: Place the assembled sandwiches in the skillet. Grill each side for 3 to 4 minutes, pressing down lightly to ensure even cooking. Cook until the bread is golden brown and the cheese inside has melted completely.
Serve Warm: Remove from heat and cut the sandwiches if desired. Serve with extra barbecue sauce on the side for dipping.

Notes

Use leftover smoked or slow-cooked brisket for the best smoky flavor.
For extra crunch and flavor, add a slice of tomato.
Swap Monterey Jack for pepper jack cheese to add more heat.
To achieve crispier edges, grill the sandwiches slowly on medium-low heat.